Decreased testosterone production causes the levels of testosterone in the blood to decline. Testosterone production declines partly because the number of Leydig cells in the testes decline with ageing. This also appears to be related to changes in the hypothalamus and pituitary glands.
The testosterone produced in an ageing man’s body is also less efficient in performing its functions. This is because older men produce more of a hormone called “sex hormone binding globulin”, which binds to testosterone and reduces the amount available to fulfil its functions. Thus, while testosterone production declines by only around 1% each year, there is a 2–3% per year reduction in the amount of testosterone available to support the male sex drive and secondary sex characteristics.
The numerous challenges the male body faces in maintaining testosterone levels whilst ageing sometimes lead to testosterone deficiency. Sex hormones are key anabolic factors, which is why their decline is associated with loss of lean muscle mass, increased abdominal fat, loss of drive, libido and stamina, which inevitably impacts quality of life.
Data from surveys conducted in other developed countries indicate that around 20% of men aged > 50 years have either low levels of testosterone in their blood, or exhibit symptoms of testosterone deficiency (e.g. excessive breast growth, loss of facial hair, rising voice).
The decrease in testosterone production is at the root of all andropause symptoms, including fatigue, depression, mood swings and loss of libido. Adding supplements like Tesnor® to one’s daily dietary intake can help to keep testosterone levels stable, bringing much relief to men suffering the symptoms of andropause.